The use of cannabis for ritual or medicinal purposes can be traced to prehistory, although today its use is controversial. Cannabinoids, the active constituents of cannabis, were first discovered in the 1940s but it wasn’t until the 1980s that the…
Blog Archives
Purinergic Receptors in the Balance
P2X7 receptors are cation-permeable, ATP-gated ion channels found on cells of immunological origin, including peripheral macrophages and glial cells in the CNS. Studies in P2X7 receptor knockout mice have suggested a specific role in inflammatory and neuropathic pain states, and…
Prostatic Acid Phosphatase: Long Lasting Pain Relief
Until very recently, prostatic acid phophatase (PAP) was thought to be a secreted protein found only in the prostate and used as a diagnostic marker for prostate cancer. Little was known about the function of PAP in vivo, or which…
