Comments for Drug Discovery Opinion

Comment on Exploiting Bioenergetic Differences to Stop GVHD by Barry Bunin

Barry Bunin — Fri, 11 May 2012 17:42:28 +0000

This was the benzodiazepine that I (Barry Bunin) synthesized first at UC Berkeley in the Ellman Group using solid phase synthesis. I still remember first scaling it up:

http://www.linkedin.com/in/collaborativediscovery

Glad to see it getting some news.

Comment on Role for HDAC3 in Friedreich’s Ataxia by antonio

antonio — Fri, 04 May 2012 16:22:12 +0000

Nina,
no se exactamente de lo què està usted hablando, pero mi correo – por si a caso quisiera enviarme algo realmente interesante sobre productos eficaces para la Friedreich , aunque lo dude – es : deba1960@libero.it
Antonio

Comment on Role for HDAC3 in Friedreich’s Ataxia by nina

nina — Tue, 24 Apr 2012 07:23:49 +0000

Estoy leyendo sus escritos , les enviare información sobre un producto., basado en azufre., con pruebas de regenracion impresionantes., se que les seran de utilidad ..Dios en ustedes porfa. dejenme un correo

Comment on One Step Nearer to Taxol by admin

admin — Mon, 23 Apr 2012 09:54:03 +0000

The picture was intended to represent bacterial generation of Taxol.

Comment on One Step Nearer to Taxol by LAXMI

LAXMI — Mon, 23 Apr 2012 01:17:19 +0000

What is the meaning behind the picture posted with the article.

Comment on Role for HDAC3 in Friedreich’s Ataxia by mona

mona — Fri, 23 Mar 2012 21:35:40 +0000

hello friends
see this link please:

http://www.checkorphan.org/grid/news/treatment/repligen-initiates-phase-1-clinical-trial-of-rg2833-in-patients-with-friedreich-s-ataxia-2

bye

Comment on Complement-ary Treatment for Alzheimer’s Disease? by Michael Bennett, MD

Michael Bennett, MD — Fri, 23 Mar 2012 00:55:16 +0000

Dear Sirs: Where can I purchase PMX205 for use in mouse experiments to test its effect on tumors and Alzheimer’s. Thank you for your reply.

Comment on Role for HDAC3 in Friedreich’s Ataxia by Gary

Gary — Fri, 17 Feb 2012 01:07:25 +0000

Hello Dear Mona,
Very good to hear from you, I haven’t been back to check lately because I really did think they cut us off. Thanks for the Italian trials info, I will look into your info on the subject, and check back sooner, now that I know we can all get on line. Good to hear from you, how is everything with your brother.

Comment on Role for HDAC3 in Friedreich’s Ataxia by mona

mona — Fri, 06 Jan 2012 16:31:48 +0000

Hello dear Gary
HAPPY NEW YEAR!!!!
I hope this year will be happy year for all of us.

New Clinical Trial in Friedreich’s Ataxia in ItalyFARA, January 5, 2012 — The Italian Health Ministry and the Ethics Committee ofthe San Luigi Hospital in Torino, Italy, have given investigators at the hospitalapproval to initiate a Phase I clinical trial of a new drug designed specifically totreat Friedreich’s ataxia. After additional study site preparations, this Phase I trialwill test the Repligen drug, known as RG2833, in patients with Friedreich’s ataxia.The investigators will aim to find out whether the drug is safe, and to learn moreabout its effects in Friedreich’s ataxia patients. In particular, they will determine ifRG2833 increases production of frataxin, a key protein that is diminished inpeople with Friedreich’s ataxia. Because lower frataxin levels are the base causeof Friedreich’s ataxia symptoms, it is hoped that, if RG2833 acts to increasefrataxin production, it could be beneficial to Friedreich’s ataxia patients.

BYE

Comment on Role for HDAC3 in Friedreich’s Ataxia by Gary

Gary — Sun, 01 Jan 2012 22:24:45 +0000

Where did everybody go, no one is replying on this site anymore, did they cut us all off.