Comments on: Prion Protein linked to Alzheimer’s Disease http://drugdiscoveryopinion.com/2009/03/prion-protein-linked-to-alzheimer%e2%80%99s-disease/ DDO Limited - Consultancy for Biotech and Pharma Fri, 06 Jan 2012 16:31:48 +0000 hourly 1 http://wordpress.org/?v= By: Drug Discovery Opinion » Glimepiride Potential for Treatment of Prion Diseases http://drugdiscoveryopinion.com/2009/03/prion-protein-linked-to-alzheimer%e2%80%99s-disease/comment-page-1/#comment-1349 Drug Discovery Opinion » Glimepiride Potential for Treatment of Prion Diseases Wed, 16 Dec 2009 08:48:05 +0000 http://drugdiscoveryopinion.com/?p=821#comment-1349 [...] modulation of cell-surface PrPc may also have application in Alzheimer’s disease since it is a receptor for β-amyloid oligomers. Whether glimepiride is sufficiently CNS-penetrant to be effective remains to be seen. Bookmark [...] [...] modulation of cell-surface PrPc may also have application in Alzheimer’s disease since it is a receptor for β-amyloid oligomers. Whether glimepiride is sufficiently CNS-penetrant to be effective remains to be seen. Bookmark [...]

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